Paraneoplastic Polymyositis – a Case Report
Authors: J. Latta1, J. Zámečník2, E. Ehler1
Authors - sphere of activity: 1Neurologická klinika FZS UP a Pardubická krajská nemocnice, a.s;
2Ústav patologie a molekulární medicíny, 2. LF UK a FN v Motole, Praha
Article: Cesk Slov Neurol N 2012; 75/108(1): 80-83
Category: Case Report
Number of articles displayed: 157x
Summary
Clinical findings, biochemical results and EMG investigation are important in the diagnosis of myopathy, and muscle biopsy is unavoidable for its further differentiation. In an older man with muscle pain and rapid development of muscle weakness with head-drop and dysphagia, polymyositis with focal endomysial CD8+ lymphocytic infiltrates was diagnosed on muscle biopsy. Once the patient had been hospitalized, an advanced carcinoma of the prostate and anti-Ri paraneoplastic antibodies were found. A paraneoplastic polymyositis was diagnosed, which is a rare diagnosis in patients with prostate cancer.
Key words:
dysphagia – neck muscles weakness – EMG – creatinkinase – muscle biopsy – paraneoplastic polymyositis
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