Diabetes and Schizophrenia

Authors: L. Ustohal1ihash2 ,2 ,2
Authors‘ workplace: CEITEC MU, Brno 1;  Psychiatrická klinika LF MU a FN Brno 2
Published in: Cesk Slov Neurol N 2012; 75/108(1): 111-114
Category: Treatment News


Epidemiological studies confirmed significantly higher prevalence of diabetes in patients with schizophrenia than in general population. It is supposed, that this fact is multifactorial. Some factors, such as genetic factors common for schizophrenia and diabetes, cannot be influenced, on the contrary some of them can be influenced. It is true especially for antipsychotic medication and patients‘ lifestyle. From this point of view, clozapine and olanzapine are more problematic antipsychotics, on the contrary amisulpride, aripiprazole, sertindole and ziprasidone are supposed to be safer. It is important to be informed about the risk of diabetes and other cardiometabolic complications and to regularly measure fasting glucose and other parameters, such as body mass index, fasting lipids, blood pressure and pulse du­ring the course of schizophrenia treatment and moreover to educate patients about healthy lifestyle.

Key words:
schizophrenia – diabetes – antipsychotics


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