Imaging Techniques to Evaluate Morphological Correlates of Cognitive Dysfunction in Multiple Sclerosis Patients

Authors: I. Obhlídalová 1;  M. Keřkovský2ihash2ihash4 ,3 ,3 ,3
Authors‘ workplace: Neurologická klinika LF MU a FN Brno 1;  Radiologická klinika LF MU a FN Brno 2;  CEITEC – Středoevropský technologický institut, MU, Brno 3
Published in: Cesk Slov Neurol N 2012; 75/108(2): 170-178
Category: Review Article


Cognitive dysfunction in patients with multiple sclerosis is quite common and has a great impact on the quality of patient’s social and professional life. High frequency and seve­rity of these symptoms encourage objectivization of their morphological correlates. Besides the conventional magnetic resonance imaging techniques, commonly used for the disease diagnostics and activity monitoring, alternative procedures, such as magnetization transfer imaging, functional magnetic resonance, MR spectroscopy or diffusion tensor imaging, are also available. The use of the majority of these techniques is currently rather experimental and their practical application is under intensive investigation.

Key words:
multiple sclerosis – cognitive dysfunction – magnetic resonance – magnetization transfer – functional magnetic resonance – diffusion tensor imaging – spectroscopy – positron emission tomography


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