Clinical and Imaging Parameters of Immunomodulating Therapy in Multiple Sclerosis

Authors: P. Štourač1 ,2
Authors‘ workplace: Neurologická klinika LF MU a F N Brno 1;  CEITEC – Středoevropský technologický institut MU, Brno 2
Published in: Cesk Slov Neurol N 2012; 75/108(4): 404-410
Category: Minimonography


Multiple sclerosis is an inflammatory autoimmune disorder of the central nervous system. Immunomodulating and immunosuppressive drugs have been shown to have partial efficacy but also, sometimes life-threatening, adverse effects. New agents continue to be introduced into the clinical practice and, therefore, treatment algorithm should be regularly updated, to reflect their efficacy, safety profile and evidence-based medicine.

Key words:
multiple sclerosis treatment – treatment algorithm – interferon β – glatiramer acetate –

fingolimod – natalizumab – mitoxantrone


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