Neuromodulation


Authors: V. Masopust 1;  R. Rokyta 2;  V. Beneš 1
Authors‘ workplace: Neurochirurgická klinika ÚVN – Vojenská FN Praha a 1. LF UK v Praze 1;  Ústav normální, patologické a klinické fyziologie, 3. LF UK v Praze 2
Published in: Cesk Slov Neurol N 2014; 77/110(2): 138-152
Category: Minimonography

Podpořeno projektem UK PRVOUK – P34.

Overview

Neuromodulation is a process in which several classes of neurotransmitters in the nervous system regulate diverse populations of neurons. Neuromodulation in neurosurgery is a process in which artificial devices manage the nervous system. The main neuromodulatory methods for the treatment of chronic pain are described. These include traditional neurostimulation methods, such as peripheral subcutaneous field stimulation (PSFS), peripheral nerve stimulation (PNS), spinal cord stimulation (SCS), occipital nerve stimulation (ONS) and motor cortex stimulation (MCS) as well as non-invasive methods, such as transcutaneous electric stimulation (TENS), repetitive transcranial magnetic stimulation (rTMS), and drug-releasing therapy – programmable pumps. For each method, its history, pathophysiology, indications, description of the procedure, complications and outcomes are described.

Key words:
neuromodulation – neurostimulation – chronic pain – treatment

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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Paediatric neurology Neurosurgery Neurology

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