Smoking Prevalence in Group of Central-European Patients with Narcolepsy-cataplexy, Narcolepsy without Cataplexy and Idiopathic Hypersomnia

Authors: P. Peřinová 1;  A. Wierzbicka 2;  E. Feketeová 3;  D. Kemlink 4;  P. Kovalská 1;  J. Nepožitek 1;  V. Ibarburu 1;  E. Králíková 5;  S. Nevšímalová 1;  K. Šonka 1
Authors‘ workplace: Centrum pro poruchy spánku a bdění, Neurologická klinika a Centrum klinických neurověd 1. LF UK a VFN v Praze 1;  Department of Clinical Neurophysiology, Institute of Psychiatry and Neurology, Warsaw, Poland 2;  Neurologická klinika LF UPJŠ a UN L. Pasteura Košice 3;  Neurologická klinika a Centrum klinických neurověd 1. LF UK a VFN v Praze 4;  Centrum pro závislé na tabáku, 3. interní klinika – klinika endokrinologie a metabolizmu 1. LF UK a VFN v Praze 5
Published in: Cesk Slov Neurol N 2017; 80/113(5): 561-563
Category: Original Paper


To map the prevalence of smok­ing among patients with narcolepsy-cataplexy (NC), narcolepsy without cataplexy (N) and idiopathic hypersomnia (IH) and verify whether smok­ing prevalence in NC patients is higher than in N and IH patients in Central Europe.

We asked 172 adult patients about smok­ing (111 of them with NC, 37 with N and 24 with IH) us­ing our own structured question­naire dur­ing their outpatient examination or dur­ing phone interview.

Daily smokers represented 46.8% in the NC group, 18.9% in N and 12.5% in the IH group. The prevalence of smok­ing in the N and IH group together is 16.4%, i.e. significantly lower than the prevalence in the NC group (p = 0.0006, two-sided Fisher test).

The prevalence of daily smok­ing among patients with NC is more than twice as high as in the Czech general adult population (18%), and higher than smok­ing prevalence among N and IH patients together.

Key words:
narcolepsy-cataplexy – narcolepsy without cataplexy – idiopathic hypersomnia – hypocretin/orexin – addiction – smoking – nicotine

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.

Chinese summary - 摘要

发作性睡病 - 猝倒症、无猝倒嗜睡症和先天性嗜睡症中欧患者的吸烟率


探讨发作性睡病 - 猝倒症(NC),无猝倒嗜睡症(N)和先天性嗜睡症(IH)患者的吸烟情况,并验证中欧地区吸烟率是否是NC组患者高于N组和IH组患者。




日常吸烟者在NC组中占46.8%,在N组中占18.9%,在IH组中占12.5%。N组和IH组吸烟率总共为16.4%,显著低于NC组(p = 0.0006,双侧Fisher检验)。




发作性睡病-猝倒症 - 无猝倒嗜睡症 - 先天性嗜睡症 -下视丘分泌素 /食欲肽 - 成瘾 - 吸烟 - 尼古丁


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