Deep brain stimulation advances in neurological diseases


Authors: Z. Košutzká 1;  A. Kušnírová 1;  I. Straka 1;  P. Matejička 1;  G. Timárová 1;  M. Minár 1;  M. Kľoc 2;  M. Novotný 3;  P. Valkovič 1,4
Authors‘ workplace: II. neurologická klinika, LF UK a UN Bratislava, SR 1;  Neurochirurgická klinika, UN – Nemocnica svätého Michala, Bratislava, SR 2;  Neurochirurgická klinika LF UK, SZU a UN Bratislava. SR 3;  Ústav normálnej a patologickej, fyziológie, Centrum experimentálnej, medicíny Slovenskej akadémie vied, Bratislava, SR 4
Published in: Cesk Slov Neurol N 2022; 85(1): 24-30
Category: Review Article
doi: 10.48095/cccsnn202224

Overview

Deep brain stimulation (DBS) is an established advanced treatment option for selected neurological disorders with failed conservative therapy. Present indications of DBS are Parkinson‘s disease, various types of dystonia and essential tremor. In recent years, the DBS indication spectrum of neurological disorders has broadened with epilepsy and other more experimental indications such as chronic cluster headache and other movement disorders (Tourette’s syndrome, Huntington’s disease). Technological hardware innovations are another important step. Almost all currently manufactured neurostimulators are MRI compatible and the longevity of batteries has significantly improved (manufacturer guarantees a longevity of 13 years and the experimental data predict up to 25 years). Directional leads became a standard practice enabling the shaping of the electrical fields and minimalization of stimulation-induced side effects. Deep brain stimulation is a safe and effective therapy option for medically refractory neurological disorders and we may predict further substantial advances in this field (time-saving automatic programming, minimalization and longevity of batteries, user-friendly patient programmers).

Keywords:

deep brain stimulation – stimulation parameters – technology innovation


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Paediatric neurology Neurosurgery Neurology

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