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Central Neurocytoma: Case Report and Review of the Literature


Authors: V. Beneš III. 1;  P. Buchvald 1;  M. Kaiser 1;  J. Mikuláštík 2;  P. Suchomel 1
Authors‘ workplace: Neurochirurgické oddělení, Krajská Nemocnice Liberec 1;  Oddělení patologie, Krajská Nemocnice Liberec 2
Published in: Cesk Slov Neurol N 2007; 70/103(6): 697-701
Category: Case Report

Poděkování: Autoři děkují za druhé čtení histologie a provedení MIB-1 prof. MUDr. S. Němečkovi, DrSc.

Overview

Central neurocytoma is a rare brain tumor predominantly encountered among young patients typically localized close to the foramen of Monro and septum pellucidum. In the absence of atypical histology, the prognosis after complete resection is usually excellent. We present a case of a 30 years old man with mild hemiparesis which led to the diagnosis of a tumor of the third and both lateral ventricles. The patient underwent partial tumor resection in two surgeries. Histologically the tumor resembled oligodendroglioma, however the cells were imunoreactive for synaptophysin. MIB-1 proliferative index was higher than 3%. On the basis of these findings, diagnosis of atypical central neurocytoma was made. The patient is symptom-free 18 months after the first surgery, residual tumor is closely observed. At the first sign of progression the patient will recieve radiotherapy. Apart from the case report we review the literature and discuss clinical and therapeutical aspects of this tumor.

Key words:
brain neoplasm – neurocytoma – intraventricular tumor – radiation therapy – synaptophysin


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Labels
Paediatric neurology Neurosurgery Neurology

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Czech and Slovak Neurology and Neurosurgery

Issue 6

2007 Issue 6

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