Recommendati ons for the Di agnosis and Management of Alzheimer’s Dise ase and Other Disorders Associ ated with Dementi a

Authors: P. Ressner 1;  J. Hort 2;  I. Rektorová 3;  A. Bartoš 4,5;  R. Rusina 6,7;  V. Línek 8;  K. She ardová 3;  Za Sekci Kognitivní Ne urologi e České Ne urologické Společnosti J. E. P.
Authors‘ workplace: Ne urologické oddělení, Nemocnice s polikliniko u v Novém Jičíně 1;  Ne urologická klinika 2. LF UK a FN v Motole, Praha 2;  I. ne urologická klinika LF MU, FN u sv. Anny v Brně 3;  Ne urologická klinika 3. LF UK a FN Královské Vinohrady, Praha 4;  Psychi atrické centrum Praha 5;  Ne urologická klinika FTNsP, Praha 6;  Institut postgraduálního vzdělávání ve zdravotnictví, Praha 7;  Ne urologická klinika 1. LF UK, VFN, Praha 8
Published in: Cesk Slov Neurol N 2008; 71/104(4): 494-501
Category: Recommendation


Backgro und:
The aim of this guideline for di agnosis of dementi a is to present a peer- revi ewed and evidence‑based statement in order to guide the practice of ne urologists, geri atrici ans, psychi atrists, and other speci alised physici ans responsible for the care of pati ents with dementi a. The main focus is the di agnosis of Alzheimer’s dise ase, but many of the recommendati ons apply to dementi a disorders in general.

The materi al is derived from a revisi on of the Europe an Federati on of Ne urological Soci eti es (EFNS) guidelines and it is assembled with current findings and notati ons particular to Czech specifics. Evidence from original rese arch reports, meta analyses and systematic revi ews published before Janu ary 2007 were considered in the writing of these guidelines.

The aim in the writing of this guideline was to propose a recommended di agnostic algorithm for Alzheimer’s dise ase, vascular dementi a, frontotemporal dementi a, Parkinson’s dise ase with dementi a, and dementi a with Lewy bodi es. It also contains informati on abo ut clinical di agnostics, blo od tests, ne uro imaging, analysis of the cerebrospinal fluid, genetic tests, bi opsy, informing of di agnosis and monitoring of the behavi oral and psychological symptoms in dementi a.

Conclusi on:
This guideline may contribute to the rati onal di agnostic methods used in the most common dementi a disorders according to evidence‑based medicine.

Key words:
dementi a –  Alzheimer’s dise ase –  vascular dementi a –  di agnostics –  guidelines


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