Virtual Autopsy Performed by Magnetic Resonance Imaging – a Case Report

Authors: M. Vaněčková 1;  Z. Seidl 1,2;  B. Goldová 3;  I. Vítková 3;  J. Kotlas 4;  P. Petrovický 5;  P. Calda 6
Authors‘ workplace: Radiodiagnostická klinika, oddělení MR, 1. LF UK a VFN v Praze 1;  Vysoká škola zdravotnická, Praha 2;  Ústav patologie 1. LF UK a VFN v Praze 3;  Ústav biologie a lékařské genetiky 1. LF UK a VFN v Praze 4;  Anatomický ústav 1. LF UK v Praze 5;  Gynekologicko-porodnická klinika 1. LF UK a VFN v Praze 6
Published in: Cesk Slov Neurol N 2009; 72/105(1): 73-76
Category: Case Report


Post mortem magnetic resonance imaging (MRI) has shown to be a complementary method to autopsy in determining fetus malformation. It may even play a key role when autopsy is limited by such factors as brain autolysis, ventricular dilatation or impossibility to perform fixation of the brain. Post mortem MRI also allows for imaging the development of the fetus; this is important for a correct interpretation and deeper understanding fetus malformations. In this case report, we describe two cases of CNS malformations (corpus callosum agenesis, occipital encephalocele), where a comparison of the prenatal ultrasound, post mortem MRI and pathological-anatomical autopsy was performed. Most information was obtained by magnetic resonance; pathological-anatomical autopsy was insufficient due to autolysis (corpus callosum agenesis). Because of severe malformation in the case of encephalocele, all three diagnostic methods were in agreement.

Key words:
magnetic resonance imaging – autopsy – fetus – malformations


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Paediatric neurology Neurosurgery Neurology

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Czech and Slovak Neurology and Neurosurgery

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2009 Issue 1

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