Medication Overuse in Chronic Daily Headache Patients in the Czech Republic


Authors: J. Marková 1;  J. Mastík 2;  D. Doležil 3;  P. Dočekal 4;  I. Niedermayerová 5;  J. Rejda 6;  R. Kotas 7;  V. Lánská 8
Authors‘ workplace: Neurologické odd., Slezská nemocnice v Opavě ;  Neurologická klinika IPVZ a FTNsP, Praha 1;  I. neurologická klinika LF MU a FN u sv. Anny v Brně 2;  Neurologická klinika 3. LF UK a FN Královské Vinohrady, Praha 3;  Neurologická klinika 1. LF UK a VFN v Praze 4;  Quattromedica spol.  s r.  o., Brno 5;  Neurologické odd., Krajská zdravotní, a. s. – Nemocnice Most, o. z. 6;  Neurologická klinika LF UK a FN Plzeň 7;  Odd. statistické analýzy, IKEM, Praha 8
Published in: Cesk Slov Neurol N 2011; 74/107(1): 67-71
Category: Short Communication

Overview

The aim of our study
was to evaluate the situation in the Czech Republic among that segment of the population that uses headache medication (analgesics combined or with single compound, non-steroidal anti-inflammatory drugs [NSAIDs], dihydroergotamine, triptans, and opioids) to excess. We included patients presenting the first time between 1st January and 30th June 2008 at specialised centres for the diagnosis and treatment of headache. All the patients fulfilled criteria for medication overuse according to the International Headache Society. We acquired demographic data, assessed the headache type, and established how long the subjects had suffered, as well as the average intensity and frequency of occurrence. We assessed data from 153 patients from seven sites, 39 men and 114 women. Average age was 46 years, patients had suffered for an headaches for an average of 21 years and the average frequency was 21 days per month. One compound was overused by 62% patients; 30% of the patients overused two substances and 8% three of them. The most commonly overused medication was sumatriptan at 30%, second was ibuprofen at 23%, followed by eletriptan at 20%. Patients were using an average of 35 pills per month for an average span of four years.

Key words:
chronic daily headache – chronic migraine – medication overuse – triptans – analgesics


Sources

1. Stovner L, Hagen K, Jensen R, katsarava Z, Lipton R, Scher A et al. The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia 2007;27(3): 193–210.

2. Headache Classification Subcommittee of the International Heaeache Society. The International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004, 24 (Suppl 1): 1–160.

3. Opavský J, Keller O, Kotas R, Mastík J, Marková J, Rejda J, Waberžinek G. Česká verze revidované Mezinárodní klasifikace bolestí hlavy navržené a předložené Mezinárodní společnosti pro bolesti hlavy. Cesk Slov Neurol N 2005; 68/101(2): 133–138.

4. Doležil D. Překlad apendixu Mezinárodní klasifikace bolestí hlavy (ICHD-II) zahrnující primární bolesti hlavy. Cesk Slov Neurol N 2009; 72/105(3): 288–290.

5. Dodick DW. Clinical practise. Chronic daily headache. N Engl J Med 2006; 354(2): 158–165.

6. Scher AI, Stewart WF, Ricci JA, Lipton RB. Factors associated with the onset and remission of chronic daily headache in a population-based study. Pain 2003; 106(1–2): 81–89.

7. Olesen J, Bousser MG, Diener HC, Dodick D, First M, Goadsby PJ et al. New appendix criteria open for a broader concept of chronic migraine. Cephalalgia 2006; 26(6): 742–746.

8. Sun-Edelstein C, Bigal ME, Rapoport AM. Chronic migraine and medication overuse headache: clarifying the current International Headache Society classification criteria. Cephalalgia 2008; 29(4): 445–452.

9. Ferrari A, Coccia C, Sternieri E. Past, present and future prospects of medication-overuse headache classification. Headache 2008; 48(7): 1096–1102.

10. Créach C, Radat F, Mick G, Guegan-Massardier E, Giraud P, Guy N et al. One or several types of triptan overuse headaches? Headache 2009; 49(4): 519–528.

11. Castillo J, Muñoz P, Guitera V, Pascual J. Kaplan Award 1998: Epidemiology of chronic daily headache in the general population. Headache 1999; 39(3): 190–196.

12. Relja G, Granato A, Antonello RA, Zorzon M. Headache induced by chronic substance use: Analysis of medication overused and minimum dose required to induce headache. Headache 2004; 44(2): 148–153.

13. Bigal ME, Lipton RB. Obesity is a risk factor for transformed migraine but not chronic tension-type headache. Neurology 2006; 67(2): 252–257.

14. Couch JR, Lipton RB, Stewart WF, Scher AI. Head or neck injury increases the risk of chronic daily headache: the risk of chronic daily headache: A population-based study. Neurology 2007; 69(11): 1169–1177.

15. Silberstein S, Olesen J, Bousser MG, Diener HC, Dodick D, First M et al. The International Classsification of Headache Disorders, 2nd edition (ICHD-II) –revision of criteria for 8.2 Mediaction-overuse headache. Cephalalgia 2005; 25(6): 460–465.

16. Meskunas CA, Tepper SJ, Rapoport AM, Sheftell FD, Bigal ME. Medications associated with probable medication overuse headache reported in tertiary care headache center over a 15-year period. Headache 2006; 46(5): 766–772.

Labels
Paediatric neurology Neurosurgery Neurology

Article was published in

Czech and Slovak Neurology and Neurosurgery


2011 Issue 1

Most read in this issue

This topic is also in:


Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account