Neurological Complications of Dengue –  a Potential Threat for Central Europe

Authors: M. Salavec 1;  V. Boštíková 2;  Z. Blechová 3;  R. Sleha 2;  S. Plíšek 4;  P. Boštík 4,5
Authors‘ workplace: Klinika nemocí kožních a pohlavních LF UK a FN Hradec Králové 1;  Katedra epidemiologie, Fakulta vojenského zdravotnictví UO, Hradec Králové 2;  Klinika infekčních, parazitárních a tropických nemocí, Nemocnice Na Bulovce, Praha 3;  Klinika infekčních nemocí LF UK a FN Hradec Králové 4;  Centrum pokročilých studií, Fakulta vojenského zdravotnictví UO, Hradec Králové 5
Published in: Cesk Slov Neurol N 2013; 76/109(5): 592-595
Category: Review Article

Podpořeno grantem MO FVZ 0000502.


Dengue is an acute viral infection transmitted by Aedes mosquitoes. The disease is endemic in tropical and subtropical countries and, until recently, was considered to be exclusively an imported infection in Europe. However, this picture is changing, as there have been cases of autochtonous dengue reported in France and Croatia in 2010 and on Madeira in 2012. In addition, neurological complications are seen more frequently and in an increasing number of forms. Although this disease affects both sexes and people from all age groups, neurological complications are the most frequently diagnosed in children. Correct diagnosis can pose a problem in our geographical area due to a lack of experience with the disease on one hand and atypical disease symptomatology in our patients compared to those observed in patients from the original endemic areas on the other. Dengue can become a serious problem in our region, mainly due to gradual spread of the vector from the original areas northwards; rapid and correct diagnosis of such cases is of great importance.

Key words:
dengue fever – dengue hemorrhagic fever – dengue shock syndrome

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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Paediatric neurology Neurosurgery Neurology

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