Results of Surgical Treatment of Pituitary Adenomas in the Neurosurgery Clinic UH Olomouc


Authors: D. Krahulík 1;  L. Hrabálek 1;  M. Vaverka 1;  J. Macháč 1;  M. Hampl 1;  J. Hoza 2;  Z. Fryšák 3
Authors‘ workplace: LF UP a FN Olomouc Neurochirurgická klinika 1;  LF UP a FN Olomouc Otorinolaryngologická klinika 2;  LF UP a FN Olomouc III. interní klinika 3
Published in: Cesk Slov Neurol N 2014; 77/110(5): 608-611
Category: Short Communication

Overview

Pituitary adenomas constitute 10–15% of intracranial tumours. At present, a combination of medical, neurosurgical and radiosurgical modalities is applied to treat them. Successful treatment requires close collaboration between an endocrinologist, neurosurgeon and radiosurgeon. The authors present a series of 80 consecutive cases of pituitary adenoma treated, in cooperation with an otorhinolaryngologist, with endoscopic endonasal surgery. Nineteen secreting adenomas and 61 non-secreting tumours were treated. 70% of adenomas were macroadenomas. A follow up MRI after three months showed radical surgery in 76%. Morbidity and mortality results of this series are similar to other larger published series.

Key words:
pituitary adenoma – endonasal endo-scopic surgery – endocrinology

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


Sources

1. Nistor R. Pituitary tumours. In: Palmer JD (ed). Manual of neurosurgery. New York: Churchill Livingstone 1996: 264– 272.

2. Asa SL, Kovacs K. Clinically non‑functioning human pituitary adenomas. Can J Neurol Sci 1992; 19(2): 228– 235.

3. Horvath E, Kovacs K. Ultrastructural dia­gnosis of human pituitary adenomas. Microsc Res Tech 1992; 20(2): 107– 135.

4. Netuka D, Masopust V, Beneš V. Léčba adenomů hypofýzy. Cesk Slov Neurol N 2011; 74/ 107(3): 240– 253.

5. Webster J, Piscitelli G, Polli A, Ferrari C, Ismail I, Scanlon M. A comparison of cabergoline and bromcriptine in the treatment of hyperprolactineminic amenorrhea. N Engl J Med 1994; 331(14): 904– 909.

6. Colao A, Di Sarno A, Sarnacchiaro S, Ferone D, Di Renzo G, Merola B et al. Prolactinomas resistant to standard dopamine agonists to chronic cabergoline treatment. J Clin Endocrinol Metab 1997; 82(3): 876– 883.

7. Jane J jr, Starke R, Elzoghby M, Reames D, Payne S,Thorner M et al. Endoscopic transsphenoidal surgery for acromegaly: remission using modern criteria, complications and predictors of outcome. J Clin Endocrinol Metab 2011; 96(9): 2732– 2740. doi: 10.1210/ jc.2011‑ 0554.

8. Murad M, Fernández‑ Balsells M, Barwise A, Gallegos‑ Orozco J, Paul A, Lane M et al. Outcomes of surgical treatment for nonfunctioning pituitary adenomas: a systematic review and meta‑analysis. Clin Endocrinol (Oxf) 2010; 73(6): 777– 791. doi: 10.1111/ j.1365‑ 2265.2010.03875.x.

9. Halvorsen H, Ramm‑ Pettersen J, Josefsen R, Røn­ning P, Meling T, Berg‑ Johnsen J el al. Surgical complications after transsphenoidal microscopic and endoscopic surgery for pituitary adenoma: a onsecutive series of 506 procedures. Acta Neurochirurgica 2014; 156(3): 441– 449. doi: 10.1007/ s00701‑ 013‑ 1959‑ 7.

10. Jho HD. Endoscopic transsphenoidal surgery. J Neurooncol 2001; 54(2): 187– 195.

11. Martin C, Schwartz R, Jolesz F, Black P. Transsphenoidal resection of pituitary adenomas in an intraoperative MRI unit. Pituitary 1999; 2(2): 155– 162.

12. Laws R jr, Thapar K. Pituitary surgery. Endocrinol Metab Clin North Am 1999; 28(1): 119– 131.

13. Netuka D, Masopust V, Belšán T, Kramář F, Beneš V.One year experience with 3.0 T intraoperative MRI in pituitary surgery. Acta Neurochir Suppl 2011; 109: 157– 159. doi: 10.1007/ 978‑ 3‑ 211‑ 99651‑ 5_24.

14. Netuka D, Masopust V, Belšán T, Kramář F, Beneš V.První zkušenosti s použitím intraoperační MR při operacích adenomů hypofýzy. Cesk Slov Neurol N 2009; 72/ 105(1): 45– 50.

15. Česák T, Náhlovský J, Hosszu T, Řehák L, Látr I et al. Longitudinální sledování růstu pooperačních reziduí afunkčních adenomů hypofýzy. Cesk Slov Neurol N 2009; 72/ 105(2): 115– 124.

16. Matoušek P, Lipina R, Paleček T, Hrbáč T, Komínek P.Endoskopická transnazální chirurgie hypofýzy –  výhody spolupráce otorinolaryngologa a neurochirurga. Cesk Slov Neurol N 2010; 73/ 106(5): 542– 545.

Labels
Paediatric neurology Neurosurgery Neurology

Article was published in

Czech and Slovak Neurology and Neurosurgery

Issue 5

2014 Issue 5

Most read in this issue

This topic is also in:


Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account