Anti‑N‑ Methyl‑ D‑ Aspartate Receptor Encephalitis


Authors: Z. Libá 1;  J. Hanzalová 2;  V. Sebroňová 1;  V. Komárek 1
Authors‘ workplace: 2. LF UK a FN v Motole, Praha Klinika dětské neurologie, Ústav imunologie a neurologická klinika 1;  2. LF UK a FN v Motole, Praha Likvorová laboratoř, Ústav imunologie a neurologická klinika 2
Published in: Cesk Slov Neurol N 2014; 77/110(5): 624-630
Category: Short Communication
doi: 10.14735/amcsnn2014624

Práce byla podpořena z nadačního fondu Pohyb bez pomoci. Děvana Dimmerová se podílela na zpracování mozkomíšních moků. MU Dr. David Krýsl se společně s RNDr. Jitkou Hanzalovou aktivně podílel na zavedení vyšetření autoprotilátek spojených s encefalitidami do repertoáru likvorové laboratoře ve FN v Motole. MU Dr. Zlata Baraniková se podílela na léčbě psychiatrických příznaků onemocnění. Kolegové z Pediatrické kliniky FN v Motole zajišťovali provedení eliminačních metod.

Overview

N-methyl-D-aspartate encephalitis is a recently defined autoimmune disorder of the central nervous system. Neurological symptoms are associated with antibody-dependent internalization of NMDA receptors that leads to synapse disruption. Information about the disease, therapy and diagnosis are followed by clinical experience with our group of five patients.

Key words:
anti-NMDAR encephalitis – diagnosis – therapy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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Labels
Paediatric neurology Neurosurgery Neurology

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Czech and Slovak Neurology and Neurosurgery

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