Muscle bio­psy in 10 key points

Authors: J. Zámečník
Authors‘ workplace: Ústav patologie a molekulární medicíny, 2. LF UK a FN Motol, Praha
Published in: Cesk Slov Neurol N 2018; 81(3): 358-361
Category: Neuropathological window
doi: 10.14735/amcsnn2018358


Currently, muscle biopsy is not a first-choice diagnostic procedure in most myopathies. In suspected hereditary myopathies, muscle biopsy is only indicated when the results of the molecular biological analysis remain inconclusive or when it does not fit with the clinical phenotype of the disease. Conversely, muscle biopsy is still indicated in all cases of suspected autoimmune diseases – myositis, immune-mediated necrotizing myopathy, or vasculitis.

Key words:
muscle biopsy – myopathy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.


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Paediatric neurology Physiotherapist, university degree Neurosurgery Neurology Rehabilitation Pain management

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Czech and Slovak Neurology and Neurosurgery

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