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Muscle bio­psy in 10 key points


Authors: J. Zámečník
Authors‘ workplace: Ústav patologie a molekulární medicíny, 2. LF UK a FN Motol, Praha
Published in: Cesk Slov Neurol N 2018; 81(3): 358-361
Category: Neuropathological window
doi: https://doi.org/10.14735/amcsnn2018358

Overview

Currently, muscle biopsy is not a first-choice diagnostic procedure in most myopathies. In suspected hereditary myopathies, muscle biopsy is only indicated when the results of the molecular biological analysis remain inconclusive or when it does not fit with the clinical phenotype of the disease. Conversely, muscle biopsy is still indicated in all cases of suspected autoimmune diseases – myositis, immune-mediated necrotizing myopathy, or vasculitis.

Key words:
muscle biopsy – myopathy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.


Sources

1. Vogel H, Zamecnik J. Dia­gnostic immunohistology of muscle diseases. J Neuropath Exp Neurol 2005; 64(3): 181–193.

2. Zámečník J. Svalová bio­psie. Speciální myopatologie. In: Maříková T et al. Neurogenetika svalových dystrofií a kongenitálních myopatií. Praha: Maxdorf 2004: 142–283.

3. Carpenter S, Karpati G. Pathology of skeletal muscle. 2nd ed. Oxford: Oxford University Press 2001.

4. Karpati G (ed). Structural and molecular basis of skeletal muscle diseases. Basel: ISN Neuropath Press 2002.

5. Engel AG, Franzini-Armstrong C (eds). Myology. 3rd ed. New York: McGraw-Hill Publisher 2003.

Labels
Paediatric neurology Physiotherapist, university degree Neurosurgery Neurology Rehabilitation Pain management

Article was published in

Czech and Slovak Neurology and Neurosurgery

Issue 3

2018 Issue 3

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