Ketogenic diet –  ef­fective treatment of childhood and adolescent epilepsies

Authors: O. Horák
Authors‘ workplace: Klinika dětské neurologie LF MU a FN Brno Centrum pro epilepsie Brno
Published in: Cesk Slov Neurol N 2019; 82(1): 8-14
Category: Minimonography


Ketogenic diet has been established in the treatment of epilepsy for almost 100 years. It is ir­replaceable in paediatric epileptology, especial­ly in the treatment of myoclonic-atonic epilepsy, mak­­ing it the most ef­fective therapeutic option. With grow­­ing knowledge and implementation of the modified Atkins diet and the low glycaemic index treatment in clinical practice, the usage of ketother­apy, which is an umbrel­la term for all dietary regimes based on carbohydrate restriction and fat surplus, has been extended to all age brackets of epilepsy patients. Nevertheles­s, it is still a highly-selective ther­apy, specified for an exclusive circle of patients with perfect compliance, which is fundamental for clinical succes­s. This work aims to provide an overview of cur­rent knowledge in the field of ketother­apy and to provide clinicians with the insight into the important practical aspects of its management.

Key words:

ketotherapy – ketogenic – diet – intractable epilepsy

The author declares he has no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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