The role of physical activity in the management of patients with Parkinson‘s dis­ease

Authors: M. Schön 1,2;  I. Straka 3;  M. Sedliak 4;  J. Ukropec 1;  P. Valkovič 3,5;  B. Ukropcová 1,2,4
Authors‘ workplace: Biomedicínske centrum, Slovenská, akadémia vied, Bratislava, Slovensko 1;  Ústav patologickej fyziológie, LF UK, v Bratislave, Slovensko 2;  II. neurologická klinika LF UK a UNB, Bratislava, Slovensko 3;  Katedra športovej kinantropológie, Fakulta telesnej výchovy a športu UK, v Bratislave, Slovensko 4;  Ústav normálnej a patologickej, fyziológie, Centrum experimentálnej, medicíny, Slovenská akadémia vied, Bratislava, Slovensko 5
Published in: Cesk Slov Neurol N 2019; 82(5): 496-504
Category: Review Article
doi: 10.14735/amcsnn2019496


Parkinson‘s dis­ease (PD) is the second most prevalent neurodegenerative dis­ease. It is characterized by the progres­sive deterioration of motor as well as non-motor symp­toms, includ­­ing cognitive dysfunction, disorders of mood and sleep and gastrointenstinal symp­toms. Physical activity is a modifiable wel­l-established risk factor for PD and clinical intervention studies with regular exercise undoubtedly point to the beneficial ef­fects of aerobic as well as strength exercise train­­ing in patients with PD. Physical train­­ing improves 1. motor state, balance and functional capacity of skeletal muscles, thus reduc­­ing the risk of fal­ls; 2. physical fitness and general functional capacity of the patient; and 3. energy metabolism, reduc­­ing the risk of type 2 diabetes, which often accelerates progres­sion of PD. Moreover, physical activity and physical train­­ing improve quality of life by ameliorat­­ing both motor and non-motor symp­toms, thus slow­­ing down dis­ease progres­sion. Regular physical activity and exercise, based on individualized prescription and performed under the supervision of an experienced physician or exercise physiologist, are recom­mended as an integral part in the management of a patient with PD.

Autoři deklarují, že v souvislosti s předmětem studie nemají žádné komerční zájmy.

The authors declare they have no potential 
conflicts of interest concerning drugs, products, or services used in the study.

Redakční rada potvrzuje, že rukopis práce splnil ICMJE kritéria pro publikace zasílané do biomedicínských časopisů.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.



M. Schön1,2, I. Straka3, M. Sedliak4, J. Ukropec1, P. Valkovič3,5, 
B. Ukropcová1,2,4

Biomedicínske centrum, Slovenská akadémia vied, Bratislava, Slovensko

Ústav patologickej fyziológie, LF UK v Bratislave, Slovensko

II. neurologická klinika LF UK a UNB, Bratislava, Slovensko

Katedra športovej kinantropológie, Fakulta telesnej výchovy a športu UK v Bratislave, Slovensko

Ústav normálnej a patologickej fyziológie, Centrum experimentálnej medicíny, Slovenská akadémia vied, Bratislava, Slovensko


doc. MUDr. Barbara Ukropcová, Ph.D.

Biomedicínske centrum
Ústav experimentálnej 

Slovenská akadémia vied

Dúbravská cesta 9

845 05 Bratislava




Přijato k recenzi: 4. 3. 2019

Přijato do tisku: 2. 9. 2019


Parkinson’s disease – exercise – physical activity


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