Treatment of insomnia in the context of neuropathic pain

Authors: D. Kec 1,2;  J. Bednařík 1,2;  O. Ludka 1,3,4;  V. Hamerníková 5;  E. Vlčková 1,2
Authors‘ workplace: LF MU Brno 1;  Neurologická klinika FN Brno 2;  I. interní kardioangiologická klinika, FN u sv. Anny v Brně 3;  Mezinárodní centrum klinického, výzkumu, FN u sv. Anny v Brně 4;  Odborný psycholog, Brno 5
Published in: Cesk Slov Neurol N 2019; 82(5): 513-517
Category: Review Article
doi: 10.14735/amcsnn2019513


This sum­mary explains the complex relationship between insomnia and neuropathic pain (NP) at both neurophysiological and psychological levels. It is focused on the pos­sibilities of synergic action of the first line methods in ther­apy of insomnia and NP. In the first part we define basic terms such as „neuropathic pain“ and „insomnia“ and explain their mutual relationship between both clinical syndromes. The review focuses on the complex therapeutic approach cover­­ing both these clinical units. Attention is given to cognitive behavioral ther­apy (as the first treatment choice for chronic insomnia), and to pregabalin and gabapentin (both drugs be­­ing the first treatment choice for NP). Both of these therapeutic approaches are complementary: cognitive behavioral ther­apy has shown to have positive ef­fects in NP treatment, while pregabalin and gabapentin proved to have potential of improv­­ing sleep.

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


psychotherapy – Neuropathic pain – chronic pain – Insomnia – sleep disorder – cognitive behavioral therapy – pregabalin – gabapentin


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