Treatment of insomnia in the context of neuropathic pain


Authors: D. Kec 1,2;  J. Bednařík 1,2;  O. Ludka 1,3,4;  V. Hamerníková 5;  E. Vlčková 1,2
Authors‘ workplace: LF MU Brno 1;  Neurologická klinika FN Brno 2;  I. interní kardioangiologická klinika, FN u sv. Anny v Brně 3;  Mezinárodní centrum klinického, výzkumu, FN u sv. Anny v Brně 4;  Odborný psycholog, Brno 5
Published in: Cesk Slov Neurol N 2019; 82(5): 513-517
Category: Review Article
doi: 10.14735/amcsnn2019513

Overview

This sum­mary explains the complex relationship between insomnia and neuropathic pain (NP) at both neurophysiological and psychological levels. It is focused on the pos­sibilities of synergic action of the first line methods in ther­apy of insomnia and NP. In the first part we define basic terms such as „neuropathic pain“ and „insomnia“ and explain their mutual relationship between both clinical syndromes. The review focuses on the complex therapeutic approach cover­­ing both these clinical units. Attention is given to cognitive behavioral ther­apy (as the first treatment choice for chronic insomnia), and to pregabalin and gabapentin (both drugs be­­ing the first treatment choice for NP). Both of these therapeutic approaches are complementary: cognitive behavioral ther­apy has shown to have positive ef­fects in NP treatment, while pregabalin and gabapentin proved to have potential of improv­­ing sleep.

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.

Keywords:

neuropathic pain – chronic pain – insomnia – sleep disorder – psychotherapy – cognitive behavioral therapy – pregabalin – gabapentin


Sources

1. Fishbain DA, Cole B, Lewis JE et al. What is the evidence for chronic pain be­­ing etiological­ly as­sociated with the DSM-IV category of sleep disorder due to a general medical condition? A structured evidence-based review. Pain Med 2010; 11(2): 158– 179. doi: 10.1111/ j.1526-4637.2009.00706.x

2. Biyik Z, Solak Y, Atalay H et al. Gabapentin versus pregabalin in improv­­ing sleep quality and depres­sion in hemodialysis patients with peripheral neuropathy: a randomized prospective cros­sover trial. Internat UrolNephrol 2013; 45(3): 831– 837. doi: 10.1007/ s11255-012-0193-1.

3. Roth T, Arnold LM, Garcia-Bor­reguero D et al. Clinical review: a review of the ef­fects of pregabalin on sleep disturbance across multiple clinical conditions. Sleep Med Rev 2014; 18(3): 241– 251. doi: 10.1016/ j.smrv.2013.07.005.

4. Senba E. A key to dis­sect the triad of insomnia, chronic pain, and depres­sion. Neurosci Lett 2015; 589: 197– 199. doi: 10.1016/ j.neulet.2015.01.012.

5. Argoff CE. The coexistence of neuropathic pain, sleep, and psychiatric disorders: a novel treatment approach. Clin J Pain 2007; 23(1): 15– 22. doi: 10.1097/ 01.ajp.0000210945.27052.b3.

6. Stiefel F, Stagno D. Management of insomnia in patients with chronic pain conditions. CNS Drugs 2004; 18(5): 285– 296. doi: 10.2165/ 00023210-200418050-00002.

7. Riemann D, Baglioni C, Bas­setti C et al. European guideline for the dia­gnosis and treatment of insomnia. J Sleep Res 2017; 26(6): 675– 700. doi: 10.1111/ jsr.12594.

8. Sateia MJ, Buys­se DJ, Krystal AD et al. Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: An American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med 2017; 13(2): 307– 349. doi: 10.1378/ chest.14-0970.

9. Závěšická L. Pa­cient s nespavostí v ordinaci psychiatra. In: Příhodová I, Dostálová S (eds). Spánková medicína v kazuistikách. Praha: Mladá fronta 2016: 23– 35.

10. Šonka K, Espa-Červená K. Primární insomnie dospělých –  b) terapie. In: Raboch J, Uhlíková P, Hel­lerová P et al (eds). Psychiatrie: Doporučené postupy psychiatrické péče IV. Praha: Typografia 2014: 150– 153.

11. Attal N, Cruccu G, Baron R et al. EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision. Eur J Neurol 2010; 17(9): 1113– 1188. doi: 10.1111/ j.1468-1331.2010.02999.x.

12. Treede R, Jensen T, Campbell J et al. Neuropathic pain –  redefinition and a grad­­ing system for clinical and research purposes. Neurology 2008; 70(18): 1630– 1635. doi: 10.1212/ 01.wnl.0000282763.29778.59.

13. Neudertová H. Bolest jako syndrom. In: Hakl M (ed).Léčba bolesti: současné přístupy k léčbě bolesti a bolestivých syndromů. 2. vyd. Praha: Mladá fronta 2013: 27– 30.

14. American Academy of Sleep Medicine. The international clas­sification of sleep disorders. 3rd ed. Darien, IL: American Academy of Sleep Medicine 2014.

15. Koh K, Hamada A, Hamada Y et al. Pos­sible involvement of activated locus coeruleus– noradrenergic neurons in pain-related sleep disorders. Neurosci Lett 2015; 589: 200– 206. doi: 10.1016/ j.neulet.2014.12.002.

16. Vinik A, Emir B, Parsons B et al. Prediction of pregabalin-mediated pain response by severity of sleep disturbance in patients with painful diabetic neuropathy and post-herpetic neuralgia. Pain Med 2014; 15(4): 661– 670. doi: 10.1111/ pme.12310.

17. Druga R, Grim M, Dubový P. Anatomie centrálního nervového systému. In: Druga R (ed). Přehled drah centrálního nervového systému. 1. vyd. Praha: Galén-Karolinum 2011: 186– 219.

18. Čihák R. Funkční systémy centrálního nervového systému –  nervové dráhy. In: Čihák R (ed). Anatomie 3. 2. vyd. Praha: Grada 2004: 413– 467.

19. Claustrat B, Brun J, Chazot G. The basic physiology and pathophysiology of melatonin. Sleep Med Rev 2005; 9(1): 11– 24. doi: 10.1016/ j.smrv.2004.08.001.

20. Masters A, Pandi-Perumal SR, Seixas A et al. Melatonin, the hormone of darknes­s: from sleep promotion to ebola treatment. Brain Disord Ther 2014; 4(1): pii: 1000151. doi: 10.4172/ 2168-975X.1000151.

21. Holsboer-Trachsler E, Prieto R. Ef­fects of pregabalin on sleep in generalized anxiety disorder. Int J Neuropsychopharmacol 2013; 16(4): 925– 936. doi: 10.1016/ j.smrv.2004.08.001.

22. Bjurstrom MF, Irwin MR. Polysomnographic characteristics in nonmalignant chronic pain populations: a review of control­led studies. Sleep Med Rev 2016; 26: 74– 86. doi: 10.1016/ j.smrv.2015.03.004.

23. Von Korff M, Vitiel­lo MV, McCur­ry SM et al. Group interventions for co-morbid insomnia and osteoarthritis pain in primary care: the lifestyles cluster randomized trial design. Contemp Clin Trials 2012; 33(4): 759– 768. doi: 10.1016/ j.cct.2012.03.010.

24. Wu JQ, Appleman ER, Salazar RD et al. Cognitive behavioral ther­apy for insomnia comorbid with psychiatric and medical conditions: a meta-analysis. JAMA Intern Med 2015; 175(9): 1461– 1472. doi: 10.1001/ jamainternmed.2015.3006.

25. Tang NK, Goodchild CE, Salkovskis PM. Hybrid cognitive-behaviour ther­apy for individuals with insomnia and chronic pain: a pilot randomised control­led trial. Behav Res Ther 2012; 50(12): 814– 821. doi: 10.1016/ j.brat.2012.08.006.

26. Yoshino A, Okamoto Y, Doi M et al. Ef­fectiveness of group cognitive behavioral ther­apy for somatoform pain disorder patients in Japan: a preliminary non-case-control study. Psychiatry Clin Neurosci 2015; 69(12): 763– 772. doi: 10.1111/ pcn.12330.

27. Neudertová H. Psychoterapie pa­cientů s chronickým algickým syndromem. In: Hakl M (ed). Léčba bolesti: současné přístupy k léčbě bolesti a bolestivých syndromů. 2. vyd. Praha: Mladá fronta 2013: 128– 134.

28. Smith MT, Perlis ML, Park A al et. Comparative meta--analysis of pharmacother­apy and behavior ther­apy for persistent insomnia. Am J Psychiatry 2002; 159(1): 5– 11. doi: 10.1176/ appi.ajp.159.1.5.

29. Bednařík J, Ambler Z, Kel­ler O et al. Klinický standard pro farmakoterapii neuropatické bolesti. Cesk Slov Neurol N 2012; 75/ 108(1): 93– 101.

30. Smolík P, Pretl M, Konštacký S. Dia­gnostické a tera­peutické postupy při insomniích pro praktické lékaře. Doporučený dia­gnostický a léčebný postup pro všeobecné praktické lékaře: novelizace 2011. 10. vyd. Praha: Společnost všeobecného lékařství ČLS JEP 2011.

31. Bazil C, Dave J, Cole J et al. Pregabalin increases slow-wave sleep and may improve attention in patients with partial epilepsy and insomnia. Epilepsy Behav 2012; 23(4): 422– 425. doi: 10.1016/ j.yebeh.2012.02.005.

32. Cho YW, Song ML. Ef­fects of pregabalin in patients with hypnotic-dependent insomnia. J Clin Sleep Med 2014; 10(5): 545– 550. doi: 10.5664/ jcsm.3708.

Labels
Paediatric neurology Neurosurgery Neurology

Article was published in

Czech and Slovak Neurology and Neurosurgery

Issue 5

2019 Issue 5

Most read in this issue

This topic is also in:


Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account