Pathological magnetic resonance imaging findings in myelin oligodendrocyte glycoprotein antibody-associated disease

Authors: M. Vaněčková 1;  P. Nytrová 2
Authors‘ workplace: Oddělení MR, Radiodiagnostická klinika 1. LF UK a VFN v Praze 1;  Neurologická klinika a Centrum klinických neurověd, 1. LF UK a VFN v Praze 2
Published in: Cesk Slov Neurol N 2022; 85(4): 330-335
Category: From Clinical Praxis
doi: 10.48095/cccsnn2022330


Myelin oligodendrocyte glycoprotein antibody-associated disease is a recently identified autoimmune demyelinating disease that occurs both in adults and children. Clinical symptoms of this disease may overlap with MS or neuromyelitis optica spectrum disorders clinical presentation. In addition to the presence of serum autoantibodies, MRI findings in the brain and spinal cord are important for the diagnosis of the disease. Articles have been published describing pathological findings on MRI in an attempt to define the typical pattern of involvement for this disease and to distinguish it from other demyelinating diseases. Some patients were diagnosed under other medical conditions in the past. We would like to share our experience with MRI diagnosis of this disease and present the findings of a cohort of seven patients.


MRI – Brain – Multiple sclerosis – Spinal cord – neuromyelitis optica – myelin oligodendrocyte glycoprotein


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Paediatric neurology Neurosurgery Neurology
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