Multiple Extraneural Metastases of an Anaplastic Astrocytoma –  a Case Report

Authors: J. Hommerová 1;  J. Mraček 2;  P. Mukenšnabl 3;  L. Holubec 4;  J. Polívka 1;  V. Přibáň 2
Authors‘ workplace: LF UK a FN Plzeň Neurologická klinika 1;  LF UK a FN Plzeň Neurochirurgické oddělení 2;  LF UK a FN Plzeň Šiklův patologicko-anatomický ústav 3;  LF UK a FN Plzeň Onkologické a radioterapeutické oddělení 4
Published in: Cesk Slov Neurol N 2013; 76/109(6): 745-750
Category: Case Report


Since metastasizing of intracranial tumours outside the central nervous system is an extremely rare complication, this option tends to be omitted in clinical practice. Most frequently, metastases are formed by high-grade (malignant) gliomas. They occur most commonly in the lungs and/or pleura and, alternatively, in descending order in the kidneys, adrenal glands, pancreas, spleen, heart and skin. Higher incidence of metastases is associated with neurosurgical procedures. In this report, we describe a case of a patient with anaplastic astrocytoma and pulmonary metastases with clinical signs of pulmonary involvement definitely confirmed during autopsy that also revealed further metastases in the liver, adrenal glands and lumbar vertebrae.

Key words:
extraneural metastasis – anaplastic astrocytoma – neurosurgery – chemotherapy – radiotherapy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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Paediatric neurology Neurosurgery Neurology

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