Glioblastoma Multiforme with Simultaneous Leptomeningeal and Intramedulary Metastases – a Case Study

Authors: J. Kasík 1;  L. Loudová 1;  M. Tinková 1;  F. Charvát 2;  P. Hrabal 3
Authors‘ workplace: ÚVN – Vojenská FN Praha Neurologické oddělení 1;  ÚVN – Vojenská FN Praha Radiologické oddělení 2;  ÚVN – Vojenská FN Praha Patologicko-anatomické oddělení 3
Published in: Cesk Slov Neurol N 2014; 77/110(3): 368-372
Category: Case Report


Glioblastoma multiforme is known for its infiltrative growth into surrounding tissues as well as for dissemination of tumor cells into distant nerve structures via cerebrospinal fluid. Unlike primary brain tumors, clinical presentation of metastasis is sporadic or rare. We present a young man, who developed a clinical manifestation of a rare variant of simultaneous metastasis.

Key words:
glioblastoma multiforme – leptomeningeal metastasis – intramedullary metastasis

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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Paediatric neurology Neurosurgery Neurology

Article was published in

Czech and Slovak Neurology and Neurosurgery

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2014 Issue 3

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