Long‑term Observation of Cognitive, Emotional and Behavioral Changes in Patient with Multiple Sclerosis –  a Case Report

Authors: A. Javůrková 1;  J. Amlerová 2;  J. Raudenská 3
Authors‘ workplace: Oddělení klinické psychologie, FN Královské Vinohrady, Praha 1;  Neurologická klinika 2. LF UK Praha a FN v Motole, Praha 2;  Oddělení klinické psychologie, 2. LF UK Praha a FN v Motole, Praha 3
Published in: Cesk Slov Neurol N 2014; 77/110(4): 501-504
Category: Case Report

Podpořeno Ministerstvem zdravotnictví ČR –  RVO, FN v Motole 00064203.


The aim of the paper is to show cognitive, emotional and behavioural changes in a multiple sclerosis (MS) patient over eighteen years of observation. Case study documents maladaptation to MS diagnosis and prolonged maladaptive coping, diffusion and influence of affective components on inhibition of cognitive abilities and mental health status, the contribution of stress to development of „pseudo-relapses“ of MS, psychosocial problems and quality of life. The diagnosis of MS was devastating for the patient herself and her family. Its unpredictable course complicated adjustment and created difficulties in planning for support. Effects of disease-related stress as well as a negative side-effect of treatment led to many psychosocial problems that impaired the patient’s quality of life and affected compliance with treatment and rehabilitation. Repeated neuropsychological assessment was a part of a comprehensive diagnostic process and treatment of MS and, at the end of observation, in chronic-progressive phase of MS, was complemented with cognitive-behavioural therapy aimed at reducing burden of disease and improving the quality of life.

Key words:
multiple sclerosis – neuropsychological assessment – cognitive behavioral therapy


1. Kurtzke JF. Epidemiology of multiple sclerosis. Does this really point towards etiology? Neurol Sci 2000; 21(6): 383– 403.

2. Havrdová E. Roztroušená skleróza. Cesk Slov Neurol N 2008; 71/ 104(2): 121– 132.

3. Aronson KJ. Quality of life among persons with multiple sclerosis and their caregivers. Neurology 1997; 48(1): 74– 80.

4. Kalb R. Multiple Sclerosis: a model of Psychosocial Support. London: National Multiple Sclerosis Society 2000.

5. Motl RW, McAuley E, Snook EM, Gliottoni RC. Phy­sical activity and quality of life in multiple sclerosis: intermediary roles of disability, fatigue, mood, pain, self‑ efficacy and social support. Psychol Health Med 2009; 14(1): 111– 124. doi: 10.1080/ 13548500802241902.

6. José Sá M. Psychological aspects of multiple sclerosis. Clin Neurol Neurosurg 2008; 110(9): 868– 877.

7. Gibson J, Frank A. Supporting individuals with disabling multiple sclerosis. J R Soc Med 2002; 95(12): 580– 586.

8. Mohr DC, Likosky W, Bertagnolli A, Goodkin DE, Van Der Wende J, Dwyor P et al. Telephone‑ administered cognitive‑ behavioral therapy for the treatment of depressive symptoms in multiple sclerosis. J Consult Clin Psychol 2000; 68(2): 356– 361.

9. Tesar N, Baumhackl U, Kopp M, Günther V. Effects of psychological group therapy in patients with multiple sclerosis. Acta Neurol Scand 2003; 107(6): 394– 399.

10. Langenmayr A, Schöttes N. Psychotherapy with multiple‑ sclerosis patients. Psychol Rep 2000; 86(2): 495– 508.

Paediatric neurology Neurosurgery Neurology

Article was published in

Czech and Slovak Neurology and Neurosurgery

Issue 4

2014 Issue 4

Most read in this issue
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.


Don‘t have an account?  Create new account