Inflammatory Pseudotumor Imitating Intracranial Meningioma –  a Case Report

Authors: J. Adamkov 1;  Petra Kašparová 2 ;  T. Česák 1
Authors‘ workplace: LF UK a FN Hradec Králové Neurochirurgická klinika 1;  LF UK a FN Hradec Králové Fingerlandův ústav patologie 2
Published in: Cesk Slov Neurol N 2015; 78/111(2): 233-236
Category: Case Report


Inflammatory pseudotumour is a rare pathology of unknown aetiology, located predominantly in the orbita and lungs. Intracranial localisation is infrequent. The most frequent intracranial localisations include the cranial base and cavernous sinus. In the present paper, we present a case report of a 43-year-old woman diagnosed with a contrast-enhancing extra-axial lesion of the convexity. The patient underwent a surgery and the lesion was extirpated. The diagnosis of inflammatory pseudotumour was verified by histology. The patient is free of any symptoms one year after surgery.

Key words:
inflammatory pseudotumor – meningiom

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


1. Häusler M, Schaade L, Ramaekers VT, Doenges M, Heimann G, Sellhaus B. Inflammatory pseudotumors of the central nervous system: report of 3 cases and a literature review. Hum Pathol 2003; 34(3): 253– 262.

2. Choi BD, Hodges TR, Grant GA, Fuchs HE, Cummings TJ,Muh CR. Inflammatory pseudotumor of the lateral ventricle in a pediatric patient. Pediatr Neurosurg 2012; 48(6): 374– 378. doi: 10.1159/ 000353609.

3. Eimoto T, Yanaka M, Kurosawa M, Ikeya F. Plasma cell granuloma (inflammatory pseudotumor) of the spinal cord meninges. Report of a case. Cancer 1978; 41(5): 1929– 1936.

4. al‑ Sarraj S, Wasserberg J, Bartlett R, Bridges LR. Inflam­matory pseudotumour of the central nervous system: clinicopathological study of one case and review of the literature. Br J Neurosurg 1995; 9(1): 57– 66.

5. Chang Y, Horoupian DS, Lane B, Fross RD, Smyth LT jr, Seiling RJ. Inflammatory pseudotumor of the choroid plexus in Sjögren’s disease. Neurosurgery 1991; 29(2): 287– 290.

6. Nishioka H, Shibuya M, Nakajima S, Ohno S, Ikeda Y. A case of an intraventricular inflammatory pseudotumor presumably caused by Epstein‑Barr virus infection. Surg Neurol 2009; 71(6): 685– 688. doi: 10.1016/ j.surneu.2008.01.045.

7. Ginat DT, Bokhari A, Bhatt S, DograV. Inflammatory pseudotumors of the head and neck in pathology‑ proven cases. J Neuroradiol 2012; 39(2): 110– 115. doi: 10.1016/ j.neurad.2010.12.010.

8. Kanski JJ. Clinical ofthalmology. Orbital inflammatory diseases. 4th ed. Butterworth‑ Heinemann 2002: 566– 569.

9. Pellant A, Chrobok V, Mejzlík J. Anterior orbital meningoencephalocele. Eur Arch Otorhinolaryngol 2010; 267(9): 1475– 1476. doi: 10.1007/ s00405‑ 010‑ 1285‑ 0.

10. McCall T, Fassett DR, Lyons G, Couldwell WT. Inflammatory pseudotumor of the cavernous sinus and skull base. Neurosurg Rev 2006; 29(3): 194– 200.

11. Simone IL, Federico F, Tortorella C, Andreula CF, Zimatore GB, Giannini P et al. Localised 1H‑ MR spectroscopy for metabolic characterisation of diffuse and focal brain lesions in patients infected with HIV. J Neurol Neurosurg Psychiatry 1998; 64(4): 516– 523.

12. Weber MA, Viehoever A, Stieltjes B, Zoubaa S, Wildemann B, Baudendistel K et al. Intracerebral manifestation of an atypical monoclonal plasma cell hyperplasia depicted by MR perfusion and diffusion tensor imaging and MR spectroscopy. AJR 2005; 185(3): 784– 787.

13. Castillo M, Kwock L, Mukherji SK. Clinical applications of proton MR spectroscopy. Am J Neuroradiol 1996; 17(1): 1– 15.

14. Mineura K, Sasajima T, Kowada M, Saitoh M, Shishido F.Intracranial plasma cell granuloma evaluated by positron emission tomography. Comput Med Imaging Graph 1992; 16(1): 31– 37.

Paediatric neurology Neurosurgery Neurology

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