Neurological Manifestation of Behçet’s Disease – a Case Report

Česká verze

Authors: A. Tvaroh ¹; M. Vachová ¹; J. Bartoš ²
Authors place of work: Krajská zdravotní, a. s., Nemocnice Teplice, o. z. Neurologické oddělení ¹; Krajská zdravotní, a. s., Nemocnice Teplice, o. z. Radiologické oddělení ²
Published in the journal: Cesk Slov Neurol N 2015; 78/111(2): 223-228
Category: Kazuistika

Summary

The authors present a case report of a 41‑years ‑⁠ old woman with subacute onset of brainstem and pyramidal symptoms, and a headache. Progression of the finding on magnetic resonance suggested brainstem parenchymal inflammation, and formation of multiple focal infarcts in the brainstem and the left thalamus and posterior branch of capsula interna. Serum and cerebrospinal fluid tests showed high inflammatory markers and no evidence of any infectious agent. Detailed history revealed long‑term systemic involvement presenting as recurrent oro‑genital ulcers accompanied with eye, joint, skin and gastrointestinal disorders. Differential diagnosis of focal brain changes is discussed, including inconsistent echocardiographic findings. The clinical course with systemic involvement, laboratory findings, and response to therapy support the diagnosis of Behçet’s disease with neurological manifestation.

Key words:
Behçet’s disease –⁠ meningoencephalitis –⁠ vasculitis of the central nervous system

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

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