Options for Activation of Plastic and Adaptation Processes in the Central Nervous System using Physiotherapy in Multiple Sclerosis Patients

Authors: K. Řasová 1;  M. Procházková 1;  I. Ibrahim 2;  J. Hlinka 3,4;  J. Tintěra 2
Authors‘ workplace: Klinika rehabilitačního lékařství 3. LF UK a FN Královské Vinohrady, Praha 1;  Pracoviště radiodiagnostiky a intervenční radiologie, IKEM, Praha 2;  Národní ústav duševního zdraví, Klecany 3;  Ústav informatiky, AV ČR, v. v. i., Praha 4
Published in: Cesk Slov Neurol N 2017; 80/113(2): 150-156
Category: Review Article
doi: 10.14735/amcsnn2017150

Podporováno projektem PRVOUK P34, 260277/ SVV/ 2016, IKEM IN 00023001, GA13-23940.


The incidence of multiple sclerosis world-wide and in the Czech Republic continues to rise. It is one of the most common diseases that disables young people and excludes them from work as well as social life. Pharmacotherapy of this disease is insufficient to suppress progression. A comprehensive approach including physiotherapy is needed to reduce the symptoms of this disease. Current research aims to identify options for the most effective use of physiotherapy in the treatment of multiple sclerosis and is exploring the ways to actively and purposefully influence plastic and adaptive processes of the central nervous system. We discuss this theme in the present review article. We summarize the issue of neuroplasticity in general (and specifically in multiple sclerosis) and discuss the options for displaying plastic and adaptation processes (using functional magnetic resonance imaging in particular). Furthermore, we mention current physiotherapy approaches for multiple sclerosis and their potential impact on neuroplasticity. We summarize the results of our own research that monitors (via various imaging methods) the effect of the Motor Programs Activating Therapy, a new facilitation physiotherapy approach.

Key words:
physiotherapy techniques – central nervous system – neuroplasticity – functional magnetic resonance imaging – diffusion tensor imaging – multiple sclerosis – Motor programs activating therapy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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