Stroke Incidence in Europe –  a Systematic Review

Authors: T. Bryndziar 1,2;  P. Šedová 2–4;  R. Mikulík 2,3
Authors‘ workplace: LF MU, Brno 1;  ICRC – Mezinárodní centrum klinického výzkumu, FN u sv. Anny v Brně 2;  I. neurologická klinika LF MU a FN u sv. Anny v Brně 3;  Interní hematologická a onkologická klinika LF MU a FN Brno 4
Published in: Cesk Slov Neurol N 2017; 80/113(2): 180-189
Category: Review Article
doi: 10.14735/amcsnn2017180

Děkujeme Mgr. Jiřímu Kratochvílovi, Ph.D., za pomoc při tvorbě rešeršního dotazu pro vyhledávání článků v databázích. Děkujeme Ing. MgA. Veronice Svobodové za jazykovou úpravu textu.
Podpořeno projektem č. LQ1605 z Národního programu udržitelnosti II.


Stroke is the third most common cause of death worldwide and accounts for a significant proportion of disability in adults. According to the available data, its incidence varies substantially across different countries. However, data from many countries, including the Czech Republic, are missing, and only estimates of dubious validity are available. The aim of this project was to provide a review of available data from population studies of stroke incidence in the European countries.

A literature search was performed in the PubMed, Scopus, and Web of Science databases for all articles published in English until January 2016 that studied the incidence of stroke. We selected the studies that measured stroke incidence in the European countries and met the Sudlow and Warlow criteria. The findings of these studies are presented in a tabular form.

The database search yielded 825 articles. After removal of duplicities and application of the selection criteria, 48 studies in total were included in the review – 20 from the Western Europe, 16 from the Southern Europe, six from the Northern Europe, and six from the Eastern Europe. The lowest incidence was found in the studies from Italy – 104/100,000 (total incidence), 101/100,000 (incidence in men), and 63/100,000 (incidence in women). The highest total incidence was in a study from Ukraine – 341/100,000, the highest incidence in men was in a study from Croatia – 282/100,000, and the highest incidence in women was in a study from Portugal – 184/100,000.

The data about stroke incidence in Europe differ substantially and come from studies of various quality and age. New population-based studies of stroke incidence that will adhere to the standard criteria of quality and comparability and that will measure the incidence in the entire population are required in the Central and Eastern Europe.

Key words:
stroke – intracerebral hemorrhage – subarachnoid hemorrhage – incidence – epidemiology

The authors declare they have no potential conflicts of interest concern­ing drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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