State-of-the-Art MRI Techniques for Multiple Sclerosis

Authors: M. Keřkovský 1;  J. Stulík 1;  I. Obhlídalová 2;  P. Praksová 2;  J. Bednařík 2;  M. Dostál 1,3;  M. Kuhn 4–6;  A. Šprláková-Puková 1;  M. Mechl 1
Authors‘ workplace: Klinika radiologie a nukleární medicíny LF MU a FN Brno 1;  Neurologická klinika LF MU a FN Brno 2;  Biofyzikální ústav, LF MU a FN Brno 3;  Psychiatrická klinika LF MU a FN Brno 4;  Institut biostatistiky a analýz, LF MU, Brno 5;  Behaviorální a sociální neurovědy, CEITEC – Středoevropský technologický institut MU 6
Published in: Cesk Slov Neurol N 2017; 80(6): 647-657
Category: Review Article


Magnetic resonance imaging (MRI) is currently a key component of multiple sclerosis diagnostics. In addition to conventional techniques, based on the evaluat ion of the number and localization of visible brain and spinal cord lesions, in recent years we have seen a rapid development of new MRI techniques providing new quantitative biomarkers which better characterize pathological structural changes in central nervous system tissues occurring due to a demyelinating disease. This article summarizes new trends in MRI diagnostics of multiple sclerosis in terms of the technical foundations of different methods, possibilities for data analysis and their practical use.

Key words:
multiple sclerosis – magnetic resonance imaging – neuroimaging – diffusion tensor imaging – proton magnetic resonance spectroscopy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Supported by Czech health research council of the Ministry of Health of the Czech Republic (NV15-32133A) and by funds from the Faculty of Medicine MU to junior researcher (M. Keřkovský).


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